Hamdy was born and raised in London, United Kingdom.

Hamdy attended the University of Oxford, and graduated with a degree in law. He also holds a degree in philosophy from the University of London. After a number of low-level jobs in the media industry, Hamdy joined the consulting team at Lloyd's of London. From there, he went on to join a niche management consulting firm.

Using seed finance provided by the partners in his consulting firm, Hamdy founded a company that developed specialist online payment systems. He raised £7.5m in venture capital to launch the business. The business was later sold to one of the venture capital investors. Between 2000 and 2001, Hamdy co-wrote a weekly diary column for The Guardian on the ups and downs of being an Internet entrepreneur.

Hamdy left the corporate world to focus on building a career as a writer. As a screenwriter, he has worked with film producers on both sides of the Atlantic. He has also written for the video game industry. His debut comic The Hunter launched in December 2007. The first issue of Hamdy's second comic Leviathan was published online in 2009. In late 2009 it was announced that Hunter had been optioned for a film by Scarlet Fire Entertainment, with Hamdy providing the script. Hamdy will produce alongside Allan Loeb and Steven Pearl.